Categories

  • About
    • BSG Advantage
      • Consumable
      • Enrichment/Depletion
      • Functional Integrity
      • On-Bead Digestion
    • Business Development
    • Corporate Offices
    • News & Events
    • How to Order
  • Products
    • Hemoglobin Removal Kits
      • Hemoglobin Removal/Depletion Kits
        • HemogloBind™ Hemoglobin Deletion From Hemolyzed Serum/Plasma
        • HemoTrial™ Kit
        • HemoVoid™ - Blood Card Reagent
        • HemoVoid™ - Hemoglobin Depletion From Erythrocytes
        • HemoVoid™ - Hemoglobin Variant Enrichment From Blood
        • NuGel-HemogloBind™
      • On-Bead Sample Prep Kit for LC-MS
        • HemoVoid™ LC-MS On-Bead
    • Lipid Removal & Clarification
      • Lipid Adsorption & Clarification Reagent
        • Cleanascite™ Lipid Removal Reagent and Clarification
    • Urine Protein & Low Abundance Enrichment
      • Albumin Depletion Kits from Serum or Plasma
        • AlbuVoid™ - Albumin Depletion and Low Abundance Protein Enrichment Kit
      • General Protein Compression
        • NuGel™ NRicher™ Mx (formerly NuGel PROfessor™)
      • Hemoglobin Removal/Depletion Kits
        • HemoVoid™ - Blood Card Reagent
        • HemoVoid™ - Hemoglobin Depletion From Erythrocytes
      • On-Bead Sample Prep Kit for LC-MS
        • AlbuVoid™ LC-MS On-Bead For Serum Proteomics
      • Urine Protein Enrichment for Proteomics & Biomarkers
        • UPCK™ Urine Protein Enrichment / Concentration Kit
    • Class Specific Enrichment
      • Glycoprotein Enrichment
        • NuGel™ Glycoprotein Enrichment PBA Kit - With Phenyl Boronic Acid NuGel™ Matrix
        • NuGel™ Phenyl Boronic Acid
      • Kinase (& ATP binding proteins) enrichment reagent
        • KinaSorb™ Kinase (& ATP binding proteins) Enrichment Reagent
      • Virus and Viral Component Isolation
        • Viraffinity™ - Virus and Viral Component Isolation
        • ViraPrep™ Mammal
    • Sample Prep Mass Spectrometry
      • Lipid Adsorption & Clarification Reagent
        • Cleanascite™ Lipid Removal Reagent and Clarification
      • Protein Removal for Drug Screening & Metabolomics
        • BindPro™ For Drug Binding/Screening, Metabolomics and Protein Recovery
        • BindPro™ Metabolomics - Protein Removal & Enrichment
        • BindPro™ Trial Kit
      • SDS and Non-ionic Detergent (eg. Triton) Removal
        • SurfactAway™ SDS Removal
        • SurfactAway™ Triton Removal
      • Solid-phase Protein Extraction Reagent / DNA Isolation / Microbial & Proteoglycan Enrichment
        • ProCipitate™
    • Functional & Chemical Proteomics
      • Compound Centric Chemical Proteomics (CCDP) & Protein Compression
        • NuGel™ NRicher™ Mx (formerly NuGel PROfessor™)
      • Functional Proteomics Separations and Enrichment Kit
        • NuGel™ NRicher™ 6 (formerly NuGel PROspector™)
      • Polymer Coated Silica Affinity Immobilization Matrices
        • NuGel™ Poly-Aldehyde
        • NuGel™ Poly-Amine
        • NuGel™ Poly-Carboxy
        • NuGel™ Poly-Epoxy
        • NuGel™ Poly-Hydroxy
    • Genomic Sample Prep
      • Lipid Adsorption & Clarification Reagent
        • Cleanascite™ Lipid Removal Reagent and Clarification
      • ProCipitate™-based DNA Isolation Kits
        • ProPrep™ BAC Mini Kit
        • ProPrep™ Genomic 100 Kit
      • Solid-phase Protein Extraction Reagent / DNA Isolation / Microbial & Food Safety
        • ProCipitate™
      • Virus and Viral Component Isolation
        • Viraffinity™ - Virus and Viral Component Isolation
        • ViraPrep™ Lambda
        • ViraPrep™ Mammal
    • Accessories
      • Albuvoid Buffers
        • AlbuVoid Binding Buffer AVBB™
        • AlbuVoid Buffer Kit™
        • AlbuVoid Elution Buffer AVEB™
        • AlbuVoid Wash Buffer AVWB™
      • Gift Certificate
        • Gift Certificate
      • Hemovoid Buffers
        • HemoVoid Binding Buffer HVBB™
        • HemoVoid Buffer Kit™
        • HemoVoid Elution Buffer HVEB™
        • HemoVoid Wash Buffer HVWB™
      • Tube Filter Pack
        • Corning® Spin-X Filter
      • UPCK Buffers
        • UPCK Binding Buffer UPBB™
        • UPCK Buffer Kit™
        • UPCK Elution Buffer UPEB™
        • UPCK Wash Buffer UPWB™
  • Technical Resources
    • References
    • Publications & Reports
    • FAQs
    • Case Studies
      • Methods to selectively deplete or purify Hemoglobin from Dried Blood Spots (DBS)
      • The Utility of HemoVoid™ is Demonstrated in 3 Proteomic Investigations Identifying Potential Disease Specific Biomarkers
      • The 4 common features of our sample prep products, known as the BSG Advantage, are highlighted in a selection of journal references.
      • AlbuVoid™ Workflows Advance Cell Secretome Proteomics
      • Lipid Removal for Phenotypic Cell Response in Cancer Research
        • Biotech Support Group and Leiden University Medical Center Report on a Gene Signature Ratio derived from Stroma Liquid Biopsy™ that Predicts Survival in Colon Cancer
      • The Influence of Sample Prep Bias on LC-MS Targeted Peptide Quantification in Serum Proteomics
      • Re-imagining proteomics for developing precision medicine biomarkers of the innate immune response in SARS-CoV-2
      • Patent Application Describes New Proteomic Methods to Monitor Protease Inhibitor Function During Covid-19 Infections
      • Efficient Hemoglobin Removal Advances Red Cell Proteomics Offering Many New Insights Into Inflammation and Infectious Disease
      • The Potential for New Blood Biomarkers in the Management of COVID-19 Disease
      • Establishing the Utility of HemoVoid™ and HemogloBind™ as Enrichment Tools for Proteomic Analysis of Red Cells and Whole Blood in Parkinson’s Disease
      • Species Diversity Supported By BSG Products
      • Poster Report Describes Loss of Functional Serpin Activity In Cancer Patient Blood
      • AlbuVoid™️ PLUS & AlbuSorb™️ PLUS Evaluating Different Windows of Observation Solves The Many Challenges of Serum Proteomics
      • Tackling the Challenges of Serum Proteomics
      • Lipid Removal Sample Prep for Cell Response Applications
      • Sample Prep for Proteomic Analysis of Saliva
      • Biotech Support Group Featured in Book, "Functional Proteomics – Methods and Protocols"
      • Sample Prep Liquid Biopsy Products Suitable for Proteomic Profiling of a Variety of Body Fluid Sample Types
      • Albumin and High Abundance Depletion
      • Using HemogloBind™ as a Hemoglobin Binding Reagent
      • Diverse technologies available for researchers to selectively bind or enrich exosomes and extracellular vesicles.
      • Stroma Liquid Biopsy™ Biomarkers Profile Pan-Cancer Dysregulation of the Serum Proteome
      • Diverse Depletion and Enrichment Technologies Enhance Simplicity and Efficiency of Obtaining Quality Proteomic Information
      • Use On-Bead Digestion to Improve Time Required for Serum Digestion
      • Using AlbuVoid™ as a Serum Protein Enrichment Kit in Functional Proteomics
      • Using Cleanascite™ as a Lipid Absorption and Clarification Reagent
      • Using HemoVoid to Remove Hemoglobin Before Analysis
  • Contact
  • Liquid Biopsy

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800.935.0628
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Biotech Support Group
  • About
    • BSG Advantage
      • Consumable
      • Enrichment/Depletion
      • Functional Integrity
      • On-Bead Digestion
    • Business Development
    • Corporate Offices
    • News & Events
    • How to Order
  • Products
    • Hemoglobin Removal Kits
      • Hemoglobin Removal/Depletion Kits
        • HemogloBind™ Hemoglobin Deletion From Hemolyzed Serum/Plasma
        • HemoTrial™ Kit
        • HemoVoid™ - Blood Card Reagent
        • HemoVoid™ - Hemoglobin Depletion From Erythrocytes
        • HemoVoid™ - Hemoglobin Variant Enrichment From Blood
        • NuGel-HemogloBind™
      • On-Bead Sample Prep Kit for LC-MS
        • HemoVoid™ LC-MS On-Bead
    • Lipid Removal & Clarification
      • Lipid Adsorption & Clarification Reagent
        • Cleanascite™ Lipid Removal Reagent and Clarification
    • Urine Protein & Low Abundance Enrichment
      • Albumin Depletion Kits from Serum or Plasma
        • AlbuVoid™ - Albumin Depletion and Low Abundance Protein Enrichment Kit
      • General Protein Compression
        • NuGel™ NRicher™ Mx (formerly NuGel PROfessor™)
      • Hemoglobin Removal/Depletion Kits
        • HemoVoid™ - Blood Card Reagent
        • HemoVoid™ - Hemoglobin Depletion From Erythrocytes
      • On-Bead Sample Prep Kit for LC-MS
        • AlbuVoid™ LC-MS On-Bead For Serum Proteomics
      • Urine Protein Enrichment for Proteomics & Biomarkers
        • UPCK™ Urine Protein Enrichment / Concentration Kit
    • Class Specific Enrichment
      • Glycoprotein Enrichment
        • NuGel™ Glycoprotein Enrichment PBA Kit - With Phenyl Boronic Acid NuGel™ Matrix
        • NuGel™ Phenyl Boronic Acid
      • Kinase (& ATP binding proteins) enrichment reagent
        • KinaSorb™ Kinase (& ATP binding proteins) Enrichment Reagent
      • Virus and Viral Component Isolation
        • Viraffinity™ - Virus and Viral Component Isolation
        • ViraPrep™ Mammal
    • Sample Prep Mass Spectrometry
      • Lipid Adsorption & Clarification Reagent
        • Cleanascite™ Lipid Removal Reagent and Clarification
      • Protein Removal for Drug Screening & Metabolomics
        • BindPro™ For Drug Binding/Screening, Metabolomics and Protein Recovery
        • BindPro™ Metabolomics - Protein Removal & Enrichment
        • BindPro™ Trial Kit
      • SDS and Non-ionic Detergent (eg. Triton) Removal
        • SurfactAway™ SDS Removal
        • SurfactAway™ Triton Removal
      • Solid-phase Protein Extraction Reagent / DNA Isolation / Microbial & Proteoglycan Enrichment
        • ProCipitate™
    • Functional & Chemical Proteomics
      • Compound Centric Chemical Proteomics (CCDP) & Protein Compression
        • NuGel™ NRicher™ Mx (formerly NuGel PROfessor™)
      • Functional Proteomics Separations and Enrichment Kit
        • NuGel™ NRicher™ 6 (formerly NuGel PROspector™)
      • Polymer Coated Silica Affinity Immobilization Matrices
        • NuGel™ Poly-Aldehyde
        • NuGel™ Poly-Amine
        • NuGel™ Poly-Carboxy
        • NuGel™ Poly-Epoxy
        • NuGel™ Poly-Hydroxy
    • Genomic Sample Prep
      • Lipid Adsorption & Clarification Reagent
        • Cleanascite™ Lipid Removal Reagent and Clarification
      • ProCipitate™-based DNA Isolation Kits
        • ProPrep™ BAC Mini Kit
        • ProPrep™ Genomic 100 Kit
      • Solid-phase Protein Extraction Reagent / DNA Isolation / Microbial & Food Safety
        • ProCipitate™
      • Virus and Viral Component Isolation
        • Viraffinity™ - Virus and Viral Component Isolation
        • ViraPrep™ Lambda
        • ViraPrep™ Mammal
    • Accessories
      • Albuvoid Buffers
        • AlbuVoid Binding Buffer AVBB™
        • AlbuVoid Buffer Kit™
        • AlbuVoid Elution Buffer AVEB™
        • AlbuVoid Wash Buffer AVWB™
      • Gift Certificate
        • Gift Certificate
      • Hemovoid Buffers
        • HemoVoid Binding Buffer HVBB™
        • HemoVoid Buffer Kit™
        • HemoVoid Elution Buffer HVEB™
        • HemoVoid Wash Buffer HVWB™
      • Tube Filter Pack
        • Corning® Spin-X Filter
      • UPCK Buffers
        • UPCK Binding Buffer UPBB™
        • UPCK Buffer Kit™
        • UPCK Elution Buffer UPEB™
        • UPCK Wash Buffer UPWB™
  • Technical Resources
    • References
    • Publications & Reports
    • FAQs
    • Case Studies
      • Methods to selectively deplete or purify Hemoglobin from Dried Blood Spots (DBS)
      • The Utility of HemoVoid™ is Demonstrated in 3 Proteomic Investigations Identifying Potential Disease Specific Biomarkers
      • The 4 common features of our sample prep products, known as the BSG Advantage, are highlighted in a selection of journal references.
      • AlbuVoid™ Workflows Advance Cell Secretome Proteomics
      • Lipid Removal for Phenotypic Cell Response in Cancer Research
        • Biotech Support Group and Leiden University Medical Center Report on a Gene Signature Ratio derived from Stroma Liquid Biopsy™ that Predicts Survival in Colon Cancer
      • The Influence of Sample Prep Bias on LC-MS Targeted Peptide Quantification in Serum Proteomics
      • Re-imagining proteomics for developing precision medicine biomarkers of the innate immune response in SARS-CoV-2
      • Patent Application Describes New Proteomic Methods to Monitor Protease Inhibitor Function During Covid-19 Infections
      • Efficient Hemoglobin Removal Advances Red Cell Proteomics Offering Many New Insights Into Inflammation and Infectious Disease
      • The Potential for New Blood Biomarkers in the Management of COVID-19 Disease
      • Establishing the Utility of HemoVoid™ and HemogloBind™ as Enrichment Tools for Proteomic Analysis of Red Cells and Whole Blood in Parkinson’s Disease
      • Species Diversity Supported By BSG Products
      • Poster Report Describes Loss of Functional Serpin Activity In Cancer Patient Blood
      • AlbuVoid™️ PLUS & AlbuSorb™️ PLUS Evaluating Different Windows of Observation Solves The Many Challenges of Serum Proteomics
      • Tackling the Challenges of Serum Proteomics
      • Lipid Removal Sample Prep for Cell Response Applications
      • Sample Prep for Proteomic Analysis of Saliva
      • Biotech Support Group Featured in Book, "Functional Proteomics – Methods and Protocols"
      • Sample Prep Liquid Biopsy Products Suitable for Proteomic Profiling of a Variety of Body Fluid Sample Types
      • Albumin and High Abundance Depletion
      • Using HemogloBind™ as a Hemoglobin Binding Reagent
      • Diverse technologies available for researchers to selectively bind or enrich exosomes and extracellular vesicles.
      • Stroma Liquid Biopsy™ Biomarkers Profile Pan-Cancer Dysregulation of the Serum Proteome
      • Diverse Depletion and Enrichment Technologies Enhance Simplicity and Efficiency of Obtaining Quality Proteomic Information
      • Use On-Bead Digestion to Improve Time Required for Serum Digestion
      • Using AlbuVoid™ as a Serum Protein Enrichment Kit in Functional Proteomics
      • Using Cleanascite™ as a Lipid Absorption and Clarification Reagent
      • Using HemoVoid to Remove Hemoglobin Before Analysis
  • Contact
  • Liquid Biopsy
The BSG Advantage Consumable, Enrichment/Depletion, On-Bead Digestion, & Functional Integrity Hemoglobin Removal The GOLD Standard Products Why Waste Time and Money Using Antibodies for Depletion Biotech Support Group helps enrich your proteome better. Lipid Removal & Clarification for the Most Challenging Applications ProCipitate for DNA/RNA Isolation Superior Substitute to Phenol-Chloroform Removes all interference from Hemoglobin & Proteins Raise Your Research Learn More About Industry insights on our latest projects. Pandemic Research Products that may assist in COVID-19 and ARDS research


Research Article Cites NuGel™ PBA for Proteome Analysis of Saliva


Research Article Cites HemoVoid™ in Fish Red Blood Cell Proteome Study


Biotech Support Group Presents Stroma Liquid Biopsy Cancer Data at HUPO World Congress 2017

Research Article Cites HemogloBind™ In Diabetic Complications Study


Research Article Cites HemoVoid™ in Functional Proteome Study


Research Article Cites Cleanascite™ for Analyzing Membrane Interaction Proteins


Journal Article Highlights AlbuVoid™ in Cancer Functional Proteomic Analysis


Research Article Cites HemogloBind™ in Parkinson’s Disease Study



BSG•OMx Services

  • Functional Proteomics
  • Chemical Proteomics [CCDP™]
  • Serum Proteomics LC-MS

BSG Advantage

  • Consumable
  • Enrichment/Depletion
  • Functional Integrity
  • On-Bead Digestion

Raise Your Research

Our Case Studies describe how the BSG Advantages have been adapted to all diseases and analytical platforms

  • Learn More

Raise Your Research

Click on the Case Studies below to learn more about how the BSG Consumable Advantage has been successfully employed

  • Using HemogloBind™ as a Hemoglobin Binding Reagent
  • Diverse technologies available for researchers to selectively bind or enrich exosomes and extracellular vesicles
  • Tackling the Challenges of Serum Proteomics - AlbuVoid™ PLUS - Albumin & IgG Depletion

Raise Your Research

Click on the Case Studies below to learn more about how the BSG Enrichment/Depletion Advantage has been successfully employed

  • Sample Prep Liquid Biopsy Products Suitable for Proteomic Profiling of a Variety of Body Fluid Sample Types
  • Albumin Depletion and Enrichment Technologies Enhance Efficiency and Simplicity of Achieving Quality Proteomic Information
  • Hemoglobin Depletion and Enrichment Technologies Enhance Simplicity and Efficiency of Obtaining Quality Proteomic Information

Raise Your Research

Click on the Case Studies below to learn more about how the BSG Functional Integrity Advantage has been successfully employed

  • Lipid Removal Sample Prep for Cell Response Applications
  • Using AlbuVoid™ as a Serum Protein Enrichment Kit in Functional Proteomics
  • Using HemoVoid™ to Remove Hemoglobin Before Analysis

Raise Your Research

Click on the Case Studies below to learn more about how the BSG On-Bead Digestion Advantage has been successfully employed

  • Tackling the Challenges of Serum Proteomics - AlbuVoid™ PLUS - Albumin & IgG Depletion
  • Use On-Bead Digestion to Improve Time Required for Serum Digestion

Proteomic & Genomic Sample Prep and Enrichment

Albumin & IgG Removal Kits

  • Unique surface chemistries
  • depletes Albumin 90-95%
  • Species agnostic
  • Retains function and bio-activity
Learn more

Hemoglobin Removal Kits

  • Unique surface chemistries
  • depletes Hemoglobin 90-95%
  • Species agnostic
  • Retains function and bio-activity
Learn more

Lipid Removal & Clarification

  • Extensively cited
  • Replaces hazardous hydrocarbons
  • Diverse samples
  •  
Learn more
View All Products >>

News & Events

March 22, 2023
Research Article Cites Cleanascite™ for Proteomic Screening of Novel Biomarkers in Bile

February 16, 2023
Metabolomic Analysis Method Adopts NuGel™-HemogloBind™ in Study of Adults with Epilepsy

February 9, 2023
HemogloBind™ Employed In A Nano LC−MALDI MS/MS Method for Identifying Single Mutation Hemoglobin Variants

January 31, 2023
The role of fatty acids in Multiple Myeloma Microenvironments is investigated through the use of Cleanascite™

January 27, 2023
Cleanascite™ Employed to Investigate Membrane Vesicle Influences on Bacterial Biofilms

January 12, 2023
Research Article Describes the Use of Cleanascite™ In the Purification of HDL-Bound small RNAs

January 9, 2023
A Mini-Review Describes the Analytical Aspects of Liquid chromatography – Mass spectrometry (LC-MS) Methods Aimed at Quantification of Stroma Liquid Biopsy™ Proteins in Body Fluids

January 9, 2023
Research article employed HemogloBind™ to remove analytical interferences due to Hemoglobin

January 9, 2023
Cleanascite™ Employed to Investigate Lipid Influence in Tumor-associated macrophages (TAMs)

December 19, 2022
Cleanascite™ Employed to Determine Role of Lipids in Neutrophil Trafficking to Infection Sites

November 29, 2022
Journal Article Cites HemoVoid™ in Proteomic Study of COPD

October 11, 2022
Nature Article Cites AlbuSorb™ for Analysis of Intestinal Organoids in Crohn’s Disease

September 13, 2022
Research Article Cites Viraffinity™ in Study of Viral Encephalitis

September 9, 2022
Journal Article Cites HemoVoid™ in Proteomic Study of Aging

August 29, 2022
Cleanascite™ Employed to Help Determine Role of Lipogenesis in Pulmonary Arterial Hypertension

August 28, 2022
Journal Article Highlights HemogloBind & AlbuVoid™ to Study Protein Organization in Red Blood Cells

June 24, 2022
Cleanascite™ Employed to Help Detect Tuberculosis Virulence Factors In Serum

View Our References

Case Studies

Methods to selectively deplete or purify Hemoglobin from Dried Blood Spots (DBS)

Dried blood spot (DBS) analysis offers the advantage of collecting small blood volumes without the need for phlebotomy. Mass spectrometry is now the most common technique for dried blood spot analysis. While DBS mass spectrometry has largely been for newborn screening of metabolic disorders, the role of DBS analysis by MS now encompasses many other areas of bio-analysis. In addition, specific protein(s) and proteomic profiles are now under investigation from DBS samples. We report on simple methods to either deplete Hemoglobin or as in the case of Hemoglobinopathies, isolate Hemoglobin from DBS, for a variety of research purposes.

Read More >>
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