NewsRelease
ResearchArticle Cites Cleanascite™ for Macrophage Characterization ofSebum Lipids
MONMOUTHJUNCTION, NJ,July12, 2017 -- Biotech Support Group reports on a recent researcharticle describing the simplicity and efficiency of their lipidremoval sample preparation product for the differentiation andactivation of macrophages based on a sebum lipid profile.
Thecitation is:
Lovászi,M., et al. "Sebum lipids influence macrophage polarization andactivation." BritishJournal of Dermatology(2017). doi:10.1111/bjd.15754.
Thearticle’s authors report on sebum lipids contributing to thedifferentiation, polarization and function of macrophages. In orderto determine the role of specific lipids, lipid removal wasinvestigated from supernatants of the immortalized human SZ95sebocytes, as stated, “For lipid depletion of the supernatantsCleanascite lipid clarification reagent (Biotech Support Group,Monmouth Junction, NJ, USA) was used according to the manufacturer’sinstructions. Lipids; squalene, linoleic acid, oleic acid, palmiticacid and stearic acid (Sigma-Aldrich); were replaced individuallysubsequent to lipid depletion in a concentration of 150 μM.”.The authors concluded a role for sebaceous glands in modulatingimmune responses via their secreted lipids that are of possiblepathologic and therapeutic relevance.
“Iam very pleased that this reference shows yet another sample typesuitable for the selective efficiency of Cleanascite™,that is to remove sebum lipids for subsequent analysis usingimmunoassays.” states Swapan Roy, Ph.D., President and Founderof Biotech Support Group.
Formore information visit: Cleanascite™Lipid Removal Reagent and Clarification,at
http://www.biotechsupportgroup.com/Cleanascite-Lipid-Removal-Reagent-p/x2555.htm
AboutBiotech Support Group LLC
Convergingwith cultural and technological disruptions forthcoming inhealthcare, Biotech Support Group develops methods for cost effectiveand efficient sample prep essential for these expanding markets.Following a tiered business strategy, the company continues itsgrowth in the consumable research products area supporting therapidly expanding installation of LC-MS instrument and computationalinfrastructure. For this market, key products include: AlbuVoid™and AlbuSorb™ for albumin depletion, Cleanascite™ forlipid adsorption, HemogloBind™ and HemoVoid™ forhemoglobin removal, and NuGel™ for functional proteomics. Fromthese innovations, the company has acquired knowledgebase andbiomarker intellectual property assets that support discoveries ofprotein markers from blood, with special emphasis on early detectionand personalized medical decisions for cancer patients. For moreinformation, go tohttp://www.biotechsupportgroup.com
Contact:
MatthewKuruc 732-274-2866