HemogloBind™ Cited in Pesticide Toxicology Study of Post-Mortem Changes in Blood

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HemogloBind™Cited in Pesticide Toxicology Study of Post-Mortem Changes in Blood


MONMOUTHJUNCTION, NJ, January23, 2021 -- Biotech Support Group reports on a journal articledescribing the simplicity and efficiency of their HemogloBind™sample preparation technology for the analysis of the pesticidemethomyl, and its Hemoglobin derivatives. The citation is: 


Yamagishi,Yoshikazu, Hirotaro Iwase, and Yasumitsu Ogra. "Post-MortemChanges of Methomyl in Blood with Hemoglobin."ChemicalResearch in Toxicology.


BSG_Figure 1_Schematic diagram of fractionation of blood componentsMethomylis a widely used pesticide that has been detected in many fatal casesof accidental exposure or suicide. Forensic toxicologists have beenbaffled that the blood methomyl concentration in persons who havedied of methomyl poisoning is much lower than the expectedconcentration in blood. In this study, the researchers consideredspecific methomyl hemoglobin adducts detected by liquidchromatography quadrupole time-of-flight mass spectrometry(LC-Q/TOF-MS). To help isolate Hemoglobin, the article states “Hbwas separated with HemogloBind in accordance with the manufacturersinstructions.” The authors conclude that one Hemoglobin derivative,the W-adduct could be used as a biomarker of methomyl poisoning.


Iam very pleased that our users have found still another applicationfor HemogloBind™,this time in the isolation of Hemoglobin for more in-depth analysis.Its simple protocol and compatibility with liquid chromatographyquadrupole time-of-flight mass spectrometry (LC-Q/TOF-MS) makes thispossible.” states Swapan Roy, Ph.D., President and Founder ofBiotech Support Group.


Formore information visit: HemogloBind™product page, at https://www.biotechsupportgroup.com/HemogloBind-Hemoglobin-Depletion-From-Hemolyzed-p/h0145.htm


Formore information on all of our Hemoglobin Removal Products, visit:

https://www.biotechsupportgroup.com/Hemoglobin-Removal-s/312.htm


AboutBiotech Support Group LLC

Convergingwith cultural and technological disruptions forthcoming inhealthcare, Biotech Support Group develops methods for cost effectiveand efficient sample prep essential for these expanding markets.Following a tiered business strategy, the company continues itsgrowth in the consumable research products area supporting therapidly expanding installation of LC-MS instrument and computationalinfrastructure. For this market, key products include: AlbuVoid™and AlbuSorb™ for albumin depletion, Cleanascite™ for lipidadsorption, HemogloBind™ and HemoVoid™ for hemoglobin removal,and NuGel™ for functional proteomics. From these innovations, thecompany has acquired knowledgebase and biomarker intellectualproperty assets that support discoveries of protein markers fromblood, with special emphasis on early detection and personalizedmedical decisions for cancer patients. For more information, gotohttp://www.biotechsupportgroup.com.


ForBusiness Development,contact:MatthewKuruc 732-274-2866, [email protected]

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