Omental conditioned medium (OCM)
Chen, Rain R., et al. "Targeting of lipid metabolism with a metabolic inhibitor cocktail eradicates peritoneal metastases in ovarian cancer cells." Communications Biology 2 (2019).
Nguyen, Amanda. "HDLs and LDLs in the Brain: Characterizing the Lipid Secretome of Astrocytes." The FASEB Journal 31.1_supplement (2017): 948-3.
Human serum, mouse serum or DMEM
Hong-Jai, et al.
effect of humoral milieu on the viral DNA and surface antigen
expression of hepatitis B virus (HBV) in vitro.
& Cellular Toxicology
15.2 (2019): 123-128.
Noncirculating Biological Fluids
Farina, Annarita. "Pre-fractionation of Noncirculating Biological Fluids to Improve Discovery of Clinically Relevant Protein Biomarkers." Proteomics for Biomarker Discovery. Humana Press, New York, NY, 2019. 23-37.
Astrocyte conditioned media
Sprenkle, Neil T., et al. "Endoplasmic reticulum stress is transmissible in vitro between cells of the central nervous system." Journal of neurochemistry 148.4 (2019): 516-530.Whole mouse serumDean, E. Danielle, et al. "Interrupted glucagon signaling reveals hepatic α cell axis and role for L-glutamine in α cell proliferation." Cell metabolism 25.6 (2017): 1362-1373.
Swertfeger, Debi K., et al. "Feasibility of a Plasma Bioassay to Assess Oxidative Protection of Low Density Lipoproteins by High Density Lipoproteins." Journal of Clinical Lipidology (2018).
Estrous sheep serum
Barrera, Natalibeth, Pedro C. dos Santos Neto, Federico Cuadro, Diego Bosolasco, Ana P. Mulet, Martina Crispo, and Alejo Menchaca. "Impact of delipidated estrous sheep serum supplementation on in vitro maturation, cryotolerance and endoplasmic reticulum stress gene expression of sheep oocytes." PloS one 13, no. 6 (2018): e0198742.
Extracellular vesicles (EVs) from bone marrow (BM)-derived mesenchymal stromal cells (BM-MSC)
Nguyen, Doan C., Holly C. Lewis, Chester Joyner, Vivien Warren, Haopeng Xiao, Haydn T. Kissick, Ronghu Wu, Jacques Galipeau, and F. Eun-Hyung Lee. "
Extracellular vesicles from bone marrow-derived mesenchymal stromal cells support ex vivo survival of human antibody secreting cells." Journal of extracellular vesicles 7, no. 1 (2018): 1463778.
Cell wall preparations
Isolation and Preliminary Characterization of Anti-Inflammatory Molecules from the Staphylococcal Cell Wall (Doctoral dissertation, McGill University).
Pancreatic Rough Endoplasmic Reticulum (RER) Fractions
R. T., Su, H. Y., Piplani, H., Capri, J., Whitelegge, J. P., Faull,
K. F., ... & Freeman, M. R. (2018).
Ethanol Induced Disordering of Pancreatic Acinar Cell Endoplasmic Reticulum: An ER Stress/Defective Unfolded Protein Response Model. Cellular
and Molecular Gastroenterology and Hepatology
Cells and bacterial lysates
Ahmed, Syed Mukhtar, and Ian G. Macara. "The Par3 polarity protein is an exocyst receptor essential for mammary cell survival." Nature Communications 8 (2017).
Human SZ95 sebocytes
Lovászi, M., et al. "Sebum lipids influence macrophage polarization and activation." British Journal of Dermatology (2017). doi: 10.1111/bjd.15754
Chan, DW, Mak, SL, Ngan, HYS. The significance of lipid metabolism in peritoneal metastases of ovarian cancer. The 2016 Cold Spring Harbour Asia Conference on Cancer and Metabolism, Suzhou, China, 19-23 September 2016. http://hub.hku.hk/handle/10722/235385
Taylor, Steven W., et al. "A high-throughput mass spectrometry assay to simultaneously measure intact insulin and C-peptide." Clinica Chimica Acta (2016).
Serum or Blood
Berggren, Per Olof, and Shao-Nian Yang. "Methods for treating and/or limiting development of diabetes." U.S. Patent Application No. 14/995,341.
Vesterhus, Mette, et al. "Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis." Journal of hepatology 66.6 (2017): 1214-1222.
Hauser-Davis, Rachel Ann. "Fish Bile Clean-up for Subsequent Zymography and Mass Spectrometry Proteomic Analyses." (2018).
Vesterhus, Mette, et al. "
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis." Journal of Hepatology 66.6 (2017): 1214-1222.
Laohaviroj, Marut, et al. "
A comparative proteomic analysis of bile for biomarkers of cholangiocarcinoma." Tumor Biology 39.6 (2017): 1010428317705764.
Vesterhus, Mette, Anders Holm, Johannes Roksund Hov, Ståle Nygård, Erik Schrumpf, Espen Melum, Liv Wenche Thorbjørnsen et al. "
Novel serum and bile protein markers predict primary sclerosing cholangitis disease severity and prognosis." Journal of Hepatology (2017).
Megger, Dominik A., et al. "One Sample, One Shot-Evaluation of sample preparation protocols for the mass spectrometric proteome analysis of human bile fluid without extensive fractionation." Journal of Proteomics (2016).
Lukic, Natalija, et al. "
An integrated approach for comparative proteomic analysis of human bile reveals overexpressed cancer-associated proteins in malignant biliary stenosis." Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1844.5 (2014): 1026-1033.
Danese, Elisa, et al. "
Assessment of bile and serum mucin5AC in cholangiocarcinoma: Diagnostic performance and biologic significance."Surgery (2014).
Farina, Annarita, et al. "
Bile carcinoembryonic cell adhesion molecule 6 (CEAM6) as a biomarker of malignant biliary stenoses." Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics (2013).
Boschetti, Egisto, and Pier Giorgio Righetti.
Low-Abundance Proteome Discovery: State of the Art and Protocols. Newnes, 2013.
Wang W, Ai KX, Yuan Z, Huang XY, Zhang HZ.
Different Expression of S100A8 in Malignant and Benign Gallbladder Diseases.Digestive diseases and sciences. 2012.
Hauser-Davis RA, Lima AA, Ziolli RL, Campos RC.
First-time report of metalloproteinases in fish bile and their potential as bioindicators regarding environmental contamination. Aquatic Toxicology.2012;110-111:99-106
Farina A, Dumonceau JM, Frossard JL.
Proteomic Analysis of Human Bile from Malignant Biliary Stenosis Induced by Pancreatic Cancer Journal of Proteome Research.2009; 8(1):159-69
Guerrier L, Claverol S, Finzi L et al.
Contribution of solid-phase hexapeptide ligand libraries to the repertoire of human bile proteins. Journal of Chromatography.2007;1176(1-2):192-205
Chen Bo, Zheng Jian-wei, Wang Jian-ming, et al.
Establishment and preliminary analysis of a 2-D human biliary map Chinese Journal of Hepatobiliary Surgery.2007
Chen B, Dong JQ, Chen YJ et al
Two-dimensional electrophoresis for comparative proteomic analysis of human bile.
Hepatobiliary & pancreatic diseases international.2007 Aug;6(4):402-6
Guerrier L, Claverol S, Finzi L et al
Contribution of solid-phase hexapeptide ligand libraries to the repertoire of human bile proteins.Journal of Chromatography A.2007;1176(1-2):192-205
Kristiansen TZ, Bunkenborg J, Gronborg M et al
A Proteomic Analysis of Human Bile Molecular and Cellular Proteomics.2004;3:715-728
Graeme T Clark, Paul J Russell, and Steven Westwood.
Modification without impact: a case study in clinical assay failure due to lipemia. Bioanalysis; 2012: 4,(12):1421-1428
Ben Wade, Michelle Cummins, Anthony Keyburn and Tamsyn M. Crowley. Isolation and detection of microRNA from the egg of chickens. BMC Research Notes 2016 9:283.
Myerson, J., He, L., Lanza, G., Tollefsen, D. and Wickline, S.
Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for the treatment and magnetic resonance imaging of acute thrombosis. Journal of Thrombosis and Haemostasis.2011;9:1292-1300
Thakuria D, Schmidt O, Liliensiek AK.
Field preservation and DNA extraction methods for intestinal microbial diversity analysis in earthworms. Journal of Microbiological Methods.2009;76(3):226-33
Cheng AM, Moore EE, Masuno T et al
Normal Mesenteric Lymph Blunts the Pulmonary Inflammatory Response to Endotoxin. Journal of Surgical Research.2006;136(S2):166-171
McNally T, Mackie IJ, Machin SJ et al.
Increased levels of beta 2 glycoprotein I antigen and beta 2 glycoprotein I binding antibodies are associated with a history of thromboembolic complications in patients with SLE and primary antiphospholipid syndrome British journal of rheumatology.1995 Nov;34(11):1031-6
Red Blood Cells
Antunes RF; Brandao C; Maia M; Arosa FA.
Red blood cells release factors with growth and survival bioactivities for normal and leukemic T cells. Immunology and Cell Biology.2011;89(1):111-21
Tracheal Swab Samples
Li D, Wang J, Wang R, Li Y.
A nanobeads amplified QCM immunosensor for the detection of avian influenza virus H5N1, Biosensors and Bioelectronics.2011;26(S10):4146-4154
Fu LM, Shinnick TM.
Genome-wide exploration of the drug action of capreomycin on Mycobacterium tuberculosis using Affymetrix oligonucleotide GeneChips Journal of Infection.2007;54(S3):277-284
Fu LM, Shinnick TM.
Genome-wide analysis of intergenic regions of mycobacterium tuberculosis H37Rv using affymetrix genechips. EURASIP journal on bioinformatics & systems biology.2007:23054
Tissue and Cell Culture
United States Patent Application 20170348398 entitled: "
COMPOSITIONS AND METHODS FOR DECREASING BLOOD GLUCAGON LEVELS”
Ahmed, Syed Mukhtar, and Ian G. Macara. "
The Par3 polarity protein is an exocyst receptor essential for mammary cell survival." Nature Communications 8 (2017): 14867. doi:10.1038/ncomms14867
Alhamdani MS, Schroder C, Hoheisel JD.
Analysis conditions for proteomic profiling of mammalian tissue and cell extracts with antibody microarrays. Proteomics.2010;10(17):3203-7
Czambel RK, Kharlamov A, Jones SC.
Variations of brain endothelial nitric oxide synthase concentration in rat and mouse cortex.Nitric Oxide.2010;22(S1): 51-57
McIntyre, John A., et al. "
Antiphospholipid autoantibodies as blood biomarkers for detection of early stage Alzheimer's disease." Autoimmunity0 (2015): 1-8.
Knight, Jason S., Wei Luo, Alexander A. O'Dell, Srilakshmi Yalavarthi, Wenpu Zhao, Venkataraman Subramanian, Chiao Guo et al. "
Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis." Circulation research (2014): CIRCRESAHA-113.
Palekar, Rohun U., et al. "
Thrombin-Targeted Liposomes Establish A Sustained Localized Anticlotting Barrier Against Acute Thrombosis." Molecular pharmaceutics (2013).
Lijowski M, Caruthers S, Hu G.
High-Resolution SPECT-CT/MR Molecular Imaging of Angiogenesis in the Vx2 Model Investigative Radiology.2009;44(1): 15–22
Turner JD, Langley RS, Johnston KL.
Wolbachia Lipoprotein Stimulates Innate and Adaptive Immunity through Toll-like Receptors 2 and 6 to Induce Disease Manifestations of Filariasis The Journal of Biological Chemistry.2009;284:22364-22378
Torrelles JB, DesJardin LE, MacNeil J. et al
Inactivation of Mycobacterium tuberculosis mannosyltransferase pimB reduces the cell wall lipoarabinomannan and lipomannan content and increases the rate of bacterial-induced human macrophage cell death Glycobiology.2009;19(7):743-755
Cho N, Chueh PJ, Kim C et al
Monoclonal antibody to a cancer-specific and drug-responsive hydroquinone (NADH) oxidase from the sera of cancer patients. Cancer Immunology, Immunotherapy. 2002;51(3):121-9
Shapiro S, Beenhouwer DO, Feldmesser M et al.
Immunoglobulin G Monoclonal Antibodies to Cryptococcus neoformans Protect Mice Deficient in Complement Component C3 Infect. Infection and immunity.2002;70(5):2598-604
Castro AR, Morrill We, Pope V. Lipid Removal from Human Serum Samples Clinical and diagnostic laboratory immunology.2000;7(2):197-199
Nussbaum G, Cleare W, Casadevall A et al
Epitope Location in the Cryptococcus neoformans Capsule Is a Determinant of Antibody Efficacy The Journal of experimental medicine.1997;185:685-694
Human & Plasma Cell Lines
Pan, Dipanjan, et al. "A strategy for combating melanoma with oncogenic c-Myc inhibitors and targeted nanotherapy." Nanomedicine 10.2 (2015): 241-251.
Pan, Dipanjan, et al. "Anti-Angiogenesis Therapy in the Vx2 Rabbit Cancer Model with a Lipase-cleavable Sn 2 Taxane Phospholipid Prodrug using αvβ3-Targeted Theranostic Nanoparticles." Theranostics 2014; 4(6):565-578
Srinivasan, Harish."Antibody microarray as a proteomic tool for effective diagnosis and prediction of prognosis in cancer."(2014).
Lucy E. DesJardin
Isolation of M. tuberculosis RNA from Sputum Methods in Molecular Medicine.2001;48:133-139
Beenhouwer DO, Shapiro S, Feldmesser M et al.
Both Th1 and Th2 Cytokines Affect the Ability of Monoclonal Antibodies To Protect Mice against Cryptococcus neoformans Infection and immunity.2001;69: 6445-6455
Desjardin LE, Perkins MD, Wolski K et al.
Measurement of Sputum Mycobacterium tuberculosis Messenger RNA as a Surrogate for Response to Chemotherapy American journal of respiratory and critical care medicine.1999;160(1):203-10
Template Preparation Production Sequencing Protocols. Stanford Genome Technology Center
Shiffman, Dov, et al. "
Methods for quantitation of insulin and c-peptide." U.S. Patent Application No. 15/942,188.
Iwakura Yoichiro, Kakuta Shigeru, Suzuki, Shunsuke - United States Patent Application 20130011413.
Method and Pharmaceutical Composition for Treatment of Intestinal Disease
Mcintyre, John A. United States Patent: 20120107841.
Serum Diagnostic Method, Biomarker and Kit for Early Detection and Staging of Alzheimer's Disease
Morre, James D et al. United States Patent: 20030170757.
Monoclonal antibodies specific for neoplasia-specific NADH: disulfide reductase
DJ Morre, NM McCarty, D Morre et al United States Patent: 7053188.
Monoclonal antibodies specific for neoplasia-specific NADH: disulfide reductase
David C. Jones. United States Patent: 7999084.
Devices and methods for reducing matrix effects
J Krupey - United States Patent: 5885921
Hydrophobic silica adsorbents for lipids
Vaccine Research (Cholesterol Removal From Human Serum)
Kamtchoua, Thierry, Monica Bologa, Robert Hopfer, David Neveu, Branda Hu, Xiaohua Sheng, Nicolas Corde, Catherine Pouzet, Gloria Zimmerman, and Sanjay Gurunathan.
Safety and immunogenicity of the pneumococcal pneumolysin derivative PlyD1 in a single-antigen protein vaccine candidate in adults.Vaccine (2012).
Lifang, et al. Balanced globin protein expression and heme biosynthesis improve production of human hemoglobin in Saccharomyces cerevisiae. Metabolic Engineering (2013).