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Unleashing the Power of Proteomics To Better Understand the Innate Immune Response to Infectious and Non-infectious Inflammatory Stimuli
In this case study, we describe how key regulatory elements of the innate immune response can be surveyed by proteomic analysis of serum/plasma, and how proteolysis and its regulation provides the central control function.Thus, the innate immunity proteome can become the source for new biomarkers in the clinical management of COVID-19.
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The complex etiology of Parkinson’s disease (PD) is only poorly understood. However, growing evidence now suggests that neurodegeneration in PD is not restricted to dopaminergic neurons in the brain. Rather, PD may be a systemic disease, involving peripheral tissues and may include oxidative, metabolic, or inflammatory processes. So blood based biomarkers may prove useful in early detection of PD as well as to assess the progression of disease in response to medical interventions.
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With many products and alternative strategies for depletion and enrichment, Biotech Support Group offers distinct and diverse separations tools that work with virtually all species
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Case Study: Methods to monitor the influence and potentially modulate the stromal conditioning of cancer, offers new avenues for diagnosis, personalized medicine, and therapeutic modalities.
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Both products deplete Albumin and IgG but in different ways, creating different windows of observation. Evaluating these different windows of observation solves the many challenges of serum proteomics.
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Biotech Support Group offers distinct and diverse technologies to help researchers selectively tackle the challenges of serum proteomics, in order to achieve quality results. In this case study, we validate a unique two-step workflow, AlbuVoid™ PLUS, to deplete Albumin and IgG.
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In this case study, we highlight two research articles describing Cleanascite™, a solid-phase suspension reagent ideally suited to remove lipids prior to applications involving cell response characterization.
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Biotech Support Group offers distinct and diverse technologies to help researchers selectively enrich or bind, in order to achieve quality results. In this case study, we highlight two research articles describing NuGel™ PBA glycoprotein enrichment sample preparation technology for the proteomic analysis of saliva.
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Biotech Support Group was recently highlighted in the book, "Functional Proteomics – Methods and Protocols." This authoritative and cutting-edge book, which seeks to fill in the current technology gap, features a collection of technologies developed for the study of protein function at a proteome scale, including much research work from BSG.
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By combining two complementary enrichment strategies, Biotech Support Group offers distinctive and diversified technologies to assist researchers achieve quality results by selectively enriching or binding.
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Diverse Albumin Depletion and Enrichment Technologies Enhance Efficiency and Simplicity of Achieving Quality Proteomic Information
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Validation of a unique Hemoglobin binding reagent, HemogloBind™, for whole blood, dried blood spot and hemolyzed serum.
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Two research articles demonstrate useful BSG products for exosome depletion and enrichment needs.
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Methods to monitor the influence, potentially modulating the systemic response to cancer, offer new avenues for diagnosis, personalized medicine and therapeutic modalities.
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Combining two complementary enrichment strategies, BSG offers diverse technologies for researchers to selectively bind or enrich, in order to achieve the best results.
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BSG’s methods development has led to an increased efficiency in protocols used for on-bead digestion of serum proteins, to as fast as two to four hours.
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Validation of an albumin depletion and low abundance protein enrichment kit, AlbuVoid™, for negative selection or voidance of albumin with low abundance enrichment of remainder sub-proteome from serum, plasma, tissues and culture media.
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Validation of a proteomic sample preparation technology, Cleanascite™, as a simple, yet effective high binding capacity for lipids with minimal cross-reactivity with proteins.
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Validation of a commercial resin, HemoVoid, to investigate the efficiency of hemoglobin depletion technology before analysis
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