HemogloBind™ Cited to Remove Interference from Hydrogel Particle Capture of Animal Disease Viruses
Biotech Support Group reports on a journal article describing the simplicity and efficiency of HemogloBind™, to remove Hemoglobin interference prior to virus capture using hydrogel particles coupled with chemical affinity baits.

News Release


HemogloBind™ Cited to Remove Interference from Hydrogel Particle Capture of Animal Disease Viruses


MONMOUTH JUNCTION, NJ, October 1, 2024 -- Biotech Support Group reports on a journal article describing the simplicity and efficiency of HemogloBind™, to remove Hemoglobin interference prior to virus capture using hydrogel particles coupled with chemical affinity baits.

The citation is:

Das, Amaresh, et al. "Enhanced Recovery and Detection of Highly Infectious Animal Disease Viruses by Virus Capture Using Nanotrap® Microbiome a Particles." (2024).

This study reports the use of Nanotrap® Microbiome A Particles (NMAPs) to capture and concentrate viruses from diluted suspensions to improve their recovery and sensitivity of detection by real-time PCR/RT-PCR (qPCR/RT-qPCR). Five highly infectious animal disease viruses were used in this study. NMAPs were used to capture spiked viruses from EDTA whole blood (EWB). Virus capture from EWB was partially blocked, most likely by hemoglobin (HMB), which also binds NMAPs and outcompetes the viruses. The interference effect from hemoglobin could be removed by first using HemogloBind™ (Biotech Support Group; Monmouth Junction, NJ), without interfering with virus capture.

The authors conclude that enhanced recovery and detection of viruses using NMAPs can be applicable to highly pathogenic animal viruses of agricultural importance.

I am pleased to see that the use of HemogloBind™ was necessary to remove the interference from Hemoglobin so efficiently. This reference highlights another key advantage which applies to all of our products. That is the maintenance of biological activity post-separations.states Swapan Roy, Ph.D., President and Founder of Biotech Support Group.


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Keywords: Hemoglobin depletion, HemogloBind™, Goatpox virus; sheeppox virus; lumpy skin disease virus; peste des petits ruminants virus; African swine fever virus; virus capture; nanotrap particles; virus isolation


About Biotech Support Group LLC

Converging with cultural and technological disruptions forthcoming in healthcare, Biotech Support Group develops methods for cost effective and efficient sample prep essential for expanding proteomic analysis. Following a tiered business strategy, the company continues its growth in the consumable research products area. For this market, key products include: AlbuVoid™ and AlbuSorb™ PLUS for albumin & IgG depletion, Cleanascite™ for lipid adsorption, HemogloBind™ and HemoVoid™ for hemoglobin removal, and NRicher™ for low abundance and family specific proteome enrichment. For more information, go to http://www.biotechsupportgroup.com


For business development contact: Matthew Kuruc
732-274-2866 mkuruc@biotechsupportgroup.com