NewsRelease
PatentApplication Describes HemoVoid™ To Uncover Proteomic Changes fromAutologous Blood-doping
MONMOUTHJUNCTION, NJ, January 15, 2021 -- Biotech Support Group reports on apatent application describing the simplicity and efficiency of theirhemoglobin depletion technology for human stored red blood cells. Thecitation is:
Christer,M. A. L. M., et al."Methodsfor the detection of autologous blood-doping."U.S. Patent Application No. 16/976,936.
Thepatent application relates to the identification of peptides, and thecorresponding proteins, that can be used in methods for the detectionof autologous blood doping. More specifically, the invention relatesto methods comprising tryptic digestion of samples of isolated redblood cell (RBC), specifically isolated RBC cytosol, followed bypeptide mapping using liquid chromatography tandem-mass spectroscopy(LC-MS/MS). The invention’s description states “Hemoglobindepletion was performed using HemoVoid resin, buffers and filtertubes as described by the manufacturer (Biotech Support Group) usinga standard bench-top centrifuge.”. Upon the preferable depletion ofhemoglobin, the methods enable detection of increased levels ofcertain peptides in samples from subjects that have been subjected toautologous blood doping, compared to samples from non-doped controlsubjects.
“Thereis great interest in understanding the proteomic changes in red cellsupon storage or in disease states. Being able to quantify thesechanges using LC-MS/MS is very important to help testing forautologous blood-doping and possibly other conditions. As this patentapplication describes, proteomic analysis is a very productive way touncover and measure these important changes. I am pleased that ourHemo-Void™ product is proving to be quite useful for thesepurposes” states Swapan Roy, Ph.D., President and Founder ofBiotech Support Group.
Formore information on HemoVoid™,visit:
https://www.biotechsupportgroup.com/HemoVoid-Hemoglobin-Depletion-From-Erythrocytes-p/hvk.htm
Formore information on all of our Hemoglobin Removal Products, visit:
https://www.biotechsupportgroup.com/Hemoglobin-Removal-s/312.htm
AboutBiotech Support Group LLC
Convergingwith cultural and technological disruptions forthcoming inhealthcare, Biotech Support Group develops methods for cost effectiveand efficient sample prep essential for these expanding markets. Following a tiered business strategy, the company continues itsgrowth in the consumable research products area supporting therapidly expanding installation of LC-MS instrument and computationalinfrastructure. For this market, key products include: AlbuVoid™and AlbuSorb™ for albumin depletion,Cleanascite™ for lipid adsorption, HemogloBind™ andHemoVoid™ for hemoglobin removal, and NuGel™ for functionalproteomics. From these innovations, the company has acquiredknowledgebase and biomarker intellectual property assets that supportdiscoveries of protein markers from blood, with special emphasis onearly detection and personalized medical decisions for cancerpatients. Formore information,go tohttp://www.biotechsupportgroup.com
ForBusiness Developmet, contact: Matthew Kuruc732-274-2866,
[email protected]