News Release

Biotech Support Group presented 2 posters at the ASMS 2020 Virtual Conference on Mass Spectrometry & Allied Topics

MONMOUTH JUNCTION, NJ, June 12, 2020 -- Biotech Support Group presented two posters at the ASMS 2020 Reboot, which became a virtual conference due to the pandemic. The posters were:

1)Targeted LC-MS Proteomic Methods to Monitor and Quantify Stromal Conditioning in Cancer from Blood

Matt Kuruc¹; Swapan Roy¹; Wilma Mesker²; Rob Tollenaar²; ¹Biotech Support Group LLC, Monmouth Junction, NJ; ²Leiden University Medical Center, Leiden, Netherlands

Brief description: Commercial enthusiasm continues for the prospects of measuring cancer non-invasively through liquid biopsy biomarkers. However, current biomarkers only serve to report tumor burden, which is not the full picture of progressive disease. The other largely neglected part of tumors, comes from the cooperation of the normal host response to acquired inflammation at the primary site. This stromal conditioning assists the tumor ecosystem and affects resistance to treatment and final outcomes. The innate immune system cooperates in this response, and we now report proteomic methods to monitor that influence from blood. With these methods, we aim to characterize and quantify Stroma Liquid Biopsy™ biomarkers in patient sera, to correlate to Tumor-Stroma Ratio scoring methods developed at Leiden University Medical Center (LUMC).

2)Dried blood spots for detection of autologous blood doping with targeted LC-MS/MS

Matt Kuruc¹; Swapan Roy¹; Johan Jakobsson²; Raik Wagner²; Christer Malm²; ¹Biotech Support Group (BSG) LLC, Monmouth Junction, NJ; ²Pro Test Diagnostics AB (PTD), Umeå, Sweden

Brief description: Dried blood spots (DBS) provide a cost effective transport and archival method for monitoring of changes in the red blood cell (RBC) proteome due to disease or ex vivo storage, such as cryopreservation used for autologous blood doping (ABD). PTD has developed proprietary peptides for detection of ABD. We assessed the detectability of selected peptides with DBS as archival method.

“These two posters highlight the value of collaborative partners jointly working to commercialize new biomarkers using novel proteomic sample prep products and methods. It is very exciting to share these developments with a dedicated group at the forefront of mass spectrometry research”, states Dr. Swapan Roy, Ph.D., President and Founder of Biotech Support Group.

For more information on the BSG complete line of Albumin & IgG Removal products, visit: https://www.biotechsupportgroup.com/Albumin-Removal-s/307.htm

For more information on the BSG complete line of Hemoglobin Removal products, visit:

https://www.biotechsupportgroup.com/Hemoglobin-Removal-s/312.htm

About Biotech Support Group LLC

Converging with cultural and technological disruptions forthcoming in healthcare, Biotech Support Group develops methods for cost effective and efficient sample prep essential for these expanding markets. Following a tiered business strategy, the company continues its growth in the consumable research products area supporting the rapidly expanding installation of LC-MS instrument and computational infrastructure. For this market, key products include: AlbuVoid™ and AlbuSorb™ for albumin depletion, Cleanascite™ for lipid adsorption, and HemogloBind™ and HemoVoid™ for hemoglobin removal. From these innovations, the company has acquired knowledgebase and biomarker intellectual property assets that support discoveries of protein markers from blood, with special emphasis on early detection and personalized medical decisions for cancer patients. For more information, go to https://www.biotechsupportgroup.com

Contact: Matthew Kuruc 732-274-2866 mkuruc@biotechsupportgroup.com