News Release
ColdSpring Harbor Protocols Book Cites Cleanascite™ for AscitesClarification
MONMOUTHJUNCTION, NJ,November15, 2021 -- Biotech Support Group reports on a research articledescribing the simplicity and efficiency of their lipid depletiontechnology to clarify ascites fluid to recover monoclonal antibodies.The citation is:
Greenfield,Edward A. "Inducing,collecting, and storing ascites." ColdSpring Harbor Protocols 2021.10(2021): pdb-prot103309.
Asciticfluid (also called ascites) is an intraperitoneal fluid extractedfrom mice that have developed a peritoneal tumor. For antibodyproduction, the tumor is induced by injecting hybridoma cells intothe peritoneum, which serves as a growth chamber for the cells. Thehybridoma cells grow to high densities and continue to secrete theantibody of interest, thus creating a high-titered solution ofantibodies for collection. In the TROUBLESHOOTINGsection, the book states:
Problem(Step 8): Aprecipitate of lipids and/or cryoproteins has formed.
Solution: Thismay be produced by long-term storage at 4°C. These precipitates canbe removed by centrifugation or by using Cleanascite (Biotech SupportGroup X2555) for clarification.
“Itsvery rewarding to see how Cleanascite™ can enhance cancer researchassociated with the selective removal of fatty acids. Cleanascite™is an aqueous suspension product without harmful solvents, or anyother non-specificcytotoxic effects.This ultimately helps researchers decide whether or not lipids, orfactors interacting with lipids, impart characteristic changes incells. This article exemplifies such utility.” states Swapan Roy,Ph.D., President and Founder of Biotech Support Group
Clickto visit Cleanascite™product page and ordering information
AboutBiotech Support Group LLC
Convergingwith cultural and technological disruptions forthcoming inhealthcare, Biotech Support Group develops methods for cost effectiveand efficient sample prep essential for these expanding markets.Following a tiered business strategy, the company continues itsgrowth in the consumable research products area supporting therapidly expanding installation of LC-MS instrument and computationalinfrastructure. For this market, key products include: AlbuVoid™and AlbuSorb™ for albumin depletion, Cleanascite™ for lipidadsorption, HemogloBind™ and HemoVoid™ for hemoglobin removal,the company has acquired knowledgebase and biomarker intellectualproperty assets that support discoveries of protein markers fromblood, with special emphasis on early detection and personalizedmedical decisions for Covid-19 and cancer patients. For moreinformation, go tohttp://www.biotechsupportgroup.com.
ForBusiness Development,contact:MatthewKuruc 732-274-2866, [email protected]