|
Journal Article Describes HemogloBind™ For Improved Cytokine Analysis Biotech Support Group reports on a research publication describing the simplicity and efficiency of their hemoglobin depletion products for cytokine/chemokine immunoassay measurements. News Release
Journal Article Describes HemogloBind™ For Improved Cytokine Analysis
MONMOUTH JUNCTION, NJ, May 19, 2022 -- Biotech Support Group reports on a research publication describing the simplicity and efficiency of their hemoglobin depletion products for cytokine/chemokine immunoassay measurements. The citation is:
Phillippi, Danielle T., et al. "Inhaled diesel exhaust particles result in microbiome-related systemic inflammation and altered cardiovascular disease biomarkers in C57Bl/6 male mice." Particle and fibre toxicology 19.1 (2022): 1-29. Exposure to particulate matter (PM) is a known mediator of inflammation and CVD. However, the role of inhaled traffic-generated PM on the gut microbiome and its corresponding systemic effects are not well-characterized. Thus, the study investigated exposure to inhaled diesel exhaust particles (DEP) on mice. To determine systemic inflammation, following HemogloBind™ treatment, plasma concentrations of 20 Cytokines were measured using a Mouse Cytokine/Chemokine Magnetic Bead Panel; the article stating “HemogloBind was added to plasma samples (1:1 ratio), … and centrifuged for 2 min at 9000 RPMs.” Key findings were that inhaled DEP exposure alters small intestinal microbial profiles to which play a role in systemic inflammation and early CVD biomarkers. “The large amount of hemolysis in mice plasma presents a special challenge for quantitative analysis. This article is one more example of how HemogloBind™ can reduce interference from hemoglobin, without compromising the recovery and measurement of very low concentration analytes like cytokines.” states Swapan Roy, Ph.D., President and Founder of Biotech Support Group.
Click here for more information on HemogloBind™ Click here for more information on all of our Hemoglobin Removal products
About Biotech Support Group LLC Converging with cultural and technological disruptions forthcoming in healthcare, Biotech Support Group develops methods for cost effective and efficient sample prep essential for expanding proteomic analysis. Following a tiered business strategy, the company continues its growth in the consumable research products area. For this market, key products include: AlbuVoid™ and AlbuSorb™ PLUS for albumin & IgG depletion, Cleanascite™ for lipid adsorption, and HemogloBind™ and HemoVoid™ for hemoglobin removal. From these innovations, the company has acquired knowledgebase and biomarker intellectual property assets that support discoveries of protein markers from blood, with special emphasis on early detection and personalized medical decisions for cancer patients. For more information, go to http://www.biotechsupportgroup.com
For
business development contact: |
- About
- Products
- Hemoglobin Removal Kits
- Lipid Removal & Clarification
- Urine Protein & Low Abundance Enrichment
- Class Specific Enrichment
- Sample Prep Mass Spectrometry
- Functional & Chemical Proteomics
- Genomic Sample Prep
- Accessories
- Technical Resources
- References
- Publications & Reports
- FAQs
- Case Studies
- NRicher™ Bead Platform Provides Unique Sub-Proteome Biases And Fit For Purpose Opportunities for Targeted LC-MS Quantification
- BSG Products To Assist in Analyzing Macrophage Polarization
- Ectodomain Shedding and Enrichment of the Soluble Membrane Proteome
- Investigate out of the Venn Diagram box
- Methods to selectively deplete or purify Hemoglobin from Dried Blood Spots (DBS)
- The Utility of HemoVoid™ is Demonstrated in 3 Proteomic Investigations Identifying Potential Disease Specific Biomarkers
- The 4 common features of our sample prep products, known as the BSG Advantage, are highlighted in a selection of journal references.
- AlbuVoid™ Workflows Advance Cell Secretome Proteomics
- Lipid Removal for Phenotypic Cell Response in Cancer Research
- The Influence of Sample Prep Bias on LC-MS Targeted Peptide Quantification in Serum Proteomics
- Re-imagining proteomics for developing precision medicine biomarkers of the innate immune response in SARS-CoV-2
- Patent Application Describes New Proteomic Methods to Monitor Protease Inhibitor Function During Covid-19 Infections
- Efficient Hemoglobin Removal Advances Red Cell Proteomics Offering Many New Insights Into Inflammation and Infectious Disease
- The Potential for New Blood Biomarkers in the Management of COVID-19 Disease
- Establishing the Utility of HemoVoid™ and HemogloBind™ as Enrichment Tools for Proteomic Analysis of Red Cells and Whole Blood in Parkinson’s Disease
- Species Diversity Supported By BSG Products
- Poster Report Describes Loss of Functional Serpin Activity In Cancer Patient Blood
- AlbuVoid™️ PLUS & AlbuSorb™️ PLUS Evaluating Different Windows of Observation Solves The Many Challenges of Serum Proteomics
- Tackling the Challenges of Serum Proteomics
- Lipid Removal Sample Prep for Cell Response Applications
- Sample Prep for Proteomic Analysis of Saliva
- Biotech Support Group Featured in Book, "Functional Proteomics – Methods and Protocols"
- Sample Prep Liquid Biopsy Products Suitable for Proteomic Profiling of a Variety of Body Fluid Sample Types
- Albumin and High Abundance Depletion
- Using HemogloBind™ as a Hemoglobin Binding Reagent
- Diverse technologies available for researchers to selectively bind or enrich exosomes and extracellular vesicles.
- Stroma Liquid Biopsy™ Biomarkers Profile Pan-Cancer Dysregulation of the Serum Proteome
- Diverse Depletion and Enrichment Technologies Enhance Simplicity and Efficiency of Obtaining Quality Proteomic Information
- Use On-Bead Digestion to Improve Time Required for Serum Digestion
- Using AlbuVoid™ as a Serum Protein Enrichment Kit in Functional Proteomics
- Using Cleanascite™ as a Lipid Absorption and Clarification Reagent
- Using HemoVoid to Remove Hemoglobin Before Analysis
- Blog
- Contact
- Liquid Biopsy