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NRicher™ Apo
NRicherâ„¢ Apo
 
Base Price: $595.00


Product Code: NRICHER-APOLIOPROTEINS
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Description
 

NRicher™ Apo

Enrichment of Apolipoproteins
  • Consumable chemically derived beads, species agnostic as they are not derived from antibodies
  • Enrich Apolipoproteins from sera or plasma from both animals and humans, >90% Albumin removal
  • Does not require any specialized instruments, just a standard microfuge
  • Bead format suitable for automation compatibility, please inquire
  • On-Bead digestion for LC-MS analysis, or optional elution for any functional, enzymatic, or immunoassay analysis
Apolipoproteins play a key role in atherosclerotic processes. Apo E variants are under investigation in neurological disorders, and in cancer there is evidence for modulating apolipoprotein expression. Thus, profiles of circulating apolipoproteins hold promise as biomarkers for the prediction of cardiovascular disease (CVD) and other precision medicine applications. However, clinical immunoassays are not available for most apolipoproteins, and variants require special consideration. For example, the size polymorphism of Lp(a) necessitates a need for isoform-agnostic measurement. Thus, advances in the productivity and multiplexing capacity of LC-MS/MS, offer the potential for personalized profiling by simultaneous quantification of multiple apolipoproteins and their associated variants.

The NRicher™ Apo product is dedicated to Apolipoproteins to help in these investigations. Another BSG product - Cleanascite™ binds to only lipid-bound proteins, and can be used to investigate the lipid-bound vs. unbound profile. This may provide additional granularity to CVD risk assessment.

Click Here To View NRicher™ APO Product Sheet