NewsRelease
ShortCommunication Describes Applications for Albumin Depletion
inProteomics Journal
MONMOUTHJUNCTION, NJ, September7, 2016 -- Biotech Support Group reports on a recent shortcommunication article describing the versatility of their albumin depletion technology forinvestigating the functional subproteomes of the Serpin superfamilyof protease inhibitors. The citation is:
SwapanRoy, Matthew Kuruc. TheFunctional Subproteomes of Serpin Protease Inhibitors are Now Openfor LC-MS Biomarker Discovery.MOJProteomics Bioinform 2016, 3(6): 00106
http://medcraveonline.com/MOJPB/MOJPB-03-00106.pdf
Theauthors consider that the conformational variants of the uniquefamily of protease inhibitors annotated as SERPINs, are most oftenunderrepresented in proteomic analyses. This limits understanding thecomplex regulation that this family of proteins presents to thenetworks within the protease web of interactions. Using bead-basedseparation provided by the NuGel™ family of proteomic enrichmentproducts - notably AlbuVoid™ & AlbuSorb™, the authorsdemonstrate their utility to satisfy investigations of serum SERPINs.The authors also suggest their use to develop functional profiles ofthe SERPIN Proteoform, and how those can establish relationships todisease phenotypes, gene mutations, and deregulated mechanisms.
“Iam very pleased that this article demonstrates the proteomicversatility of both of our albumin removal products. This articlesupports our belief that our bead-basedproteomic enrichment products are useful for the functional andstructural proteomic analyses necessary to characterize the manyconformational Serpin sub-populations so that they may become usefulbiomarkers for disease.”states Swapan Roy, Ph.D., President and Founder of Biotech SupportGroup.
Formore information on Albumin Removal,visit:
http://www.biotechsupportgroup.com/Albumin-Removal-Kits-s/108.htm
AboutBiotech Support Group LLC
Convergingwith cultural and technological disruptions forthcoming inhealthcare, Biotech Support Group develops methods for cost effectiveand efficient sample prep essential for these expanding markets.Following a tiered business strategy, the company continues itsgrowth in the consumable research products area supporting therapidly expanding installation of LC-MS instrument and computationalinfrastructure. For this market, key products include: AlbuVoid™and AlbuSorb™ for albumin depletion, Cleanascite™ for lipidadsorption, HemogloBind™ and HemoVoid™ for hemoglobin removal,and NuGel™ for functional proteomics. From these innovations, thecompany has acquired knowledgebase and biomarker intellectualproperty assets that support discoveries of protein markers fromblood, with special emphasis on early detection and personalizedmedical decisions for cancer patients. For more information,go to http://www.biotechsupportgroup.com
Contact:
Dr.Swapan Roy & Matthew Kuruc
BiotechSupport Group LLC
1Deer Park Drive, Suite M
MonmouthJunction NJ 08852
732-274-2866Worldwide
800-935-0628NorthAmerica
[email protected]
http://www.biotechsupportgroup.com
