Cleanascite™ Lipid Removal Reagent and Clarification

Cleanascite™ Lipid Removal Reagent and Clarification

  • A high binding capacity for lipids with minimal cross-reactivity with proteins
  • Effectively replaces chlorinated/fluorinated hydrocarbons (eg. freon) and it is environmentally friendly.
  • Helps purify antibodies, recombinant proteins, nucleic acids, proteoglycans
  • Ideal for clarifying ascites, serum, cell & tissue culture, bile and organ homogenates
  • Clarifies saliva and fecal components
  • Very low protein binding
  • Does not bind to DNA, RNA, enzymes and proteins
  • Leaves glycoproteins, antibodies, nucleic acids, hemoglobin, proteoglycans, nucleic acids, serum components(such as hormones, nutrients, globulins, clotting factors, transport proteins) alone
  • Extends the life of membrane and chromatographic columns.
  • Enrichment of delipidated tissue samples
  • Ideal for delipidation treatments for downstream processing of large-scale therapeutic proteins, enzymes and monclonal antibodies.

Cleanascite selectively removes lipids, cell debris, lipoproteins, floating fats, impurities from cohn paste, transgenic milk, egg yolk and biological samples for pretreatment of samples prior to purification. The reagent is a solid-phase, non-ionic adsorbent supplied as a suspension in saline, ready for use. Simply add, centrifuge and/or filter. The clarified supernatant is ready for subsequent downstream processing or analysis.

Click here to view Cleanascite™ Product Sheet

Thrombin-inhibiting perfluorocarbon nanoparticles provide a novel strategy for treatment and magnetic resonance imaging of acute thrombosis Journal of Thrombosis and Haemostasis J. Myerson, L. He et al 2011.

Red blood cells release factors with growth and survival bioactivities for normal and leukemic T cells Immunology and Cell Biology (2011) 89, 111–121

Dujuan Li, Jianping Wang, Ronghui Wang, Yanbin Li, Daad Abi-Ghanem, Luc Berghman, Billy Hargis, Huaguang Lu, A nanobeads amplified QCM immunosensor for the detection of avian influenza virus H5N1, Biosensors and Bioelectronics, Volume 26, Issue 10, 15 June 2011, Pages 4146-4154

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Annarita Farina, Jean-Marc Dumonceau et al. Proteomic Analysis of Human Bile from Malignant Biliary Stenosis Induced by Pancreatic Cancer Journal of Proteome Research 2009 8 (1), 159-169

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Genome-wide analysis of intergenic regions of mycobacterium tuberculosis H37Rv using affymetrix genechips. EURASIP J. Bioinformatics Syst. Biol. 2007 (January 2007)

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Chen B, Dong JQ, Chen YJ, Wang JM Two-dimensional electrophoresis for comparative proteomic analysis of human bile. Hepatobiliary Pancreat Dis Int. 2007 Aug;6(4):402-6

L. Guerrier et al Contribution of solid-phase hexapeptide ligand libraries to the repertoire of human bile proteins Journal of Chromatography A Volume 1176, Issues 1-2, 28 December 2007, Pages 192-205

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Template Preparation - Production Sequencing Protocols used at the Stanford Genome Technology Center

Increased levels of beta 2 glycoprotein I antigen and beta 2 glycoprotein I binding antibodies are associated with a history of thromboembolic complications in patients with SLE and primary antiphospholipid syndrome. McNally T, Mackie IJ, Machin SJ, et al.Br J Rheumatol. 1995;34:1031–6.

J Krupey - US Patent 5,885,921 Hydrophobic silica adsorbents for lipids

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