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US Justice Department Report Cites HemogloBind™ In Comparative Forensic Proteomics Strategies
MONMOUTH JUNCTION, NJ, — Biotech Support Group reports on a technical report prepared by the U.S. Department of Justice. The central goal of the project was to isolate and identify candidate protein biomarkers that are highly specific to individual types of biological stains of forensic utility (i.e., saliva, semen, peripheral blood, menstrual blood, vaginal secretions, and urine). The report is entitled “Isolation of Highly Specific Protein Markers for the Identification of Biological Stains: The National Criminal Justice Reference Service (NCJRS) has made this federally funded grant final report available electronically at: https://www.ncjrs.gov/pdffiles1/nij/grants/236691.pdf The report states: “Serum obtained from menstrual blood samples was typically contaminated with erythrocyte cellular components due to the lysing of fragile red blood cells that are abundant in the endometrial lining during menses. As hemoglobin comprises 32-36% of all the proteins found in red blood cells the serum from menstrual blood samples contained large quantities of hemoglobin which served to mask the detection of less abundant menstrual blood specific proteins. For this reason, hemoglobin was removed from collected serum prior to proteome fractionation through use of HemogloBind™ (Biotech Support Group, Monmouth Junction, NJ). This hemoglobin capture reagent is a solid-phase, non-ionic adsorbent product that bindsspecifically to hemoglobin allowing for the removal of 80-90% of hemoglobin from serum or red cell lysates. HemogloBind™ does not cross react with most common serum components, making it suitable for the proteomic applications of this research project.” “Here we find another use for HemogloBind™, further validating our unique surface technology approach, not based on biologicals, as being highly selective and an efficient method for the depletion of hemoglobin” states Swapan Roy, Ph.D., President and Founder of Biotech Support Group.
About Biotech Support Group LLC
Biotech Support Group LLC is a leading developer of proteomic, metabolomic, and genomic sample preparation and enrichment products. It’s principal products include: AlbuVoid™ & AlbuSorb™ for albumin depletion,Cleanascite™ for lipid adsorption and clarification, HemogloBind™ & HemoVoid™ for hemoglobin removal, NuGel™ for functional & chemical proteomics, and ProCipitate™ & ProPrep™ for nucleic acid isolation. For more information, go tohttp://www.biotechsupportgroup.com
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Wed, 08/06/2014 |
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