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Application Report: AlbuVoid™ & On-Bead Digestion – Tackling The Challenges of Serum Proteomics (LC-MS) MONMOUTH JUNCTION, NJ — Biotech Support Group reports on a new Application Report describing an improved method for on-bead digestion of serum proteins first enriched with AlbuVoid™. The application report is entitled: AlbuVoid™ & On-Bead Digestion: Tackling The Challenges Of Serum Proteomics. The report describes some of the challenges of serum protein abundances and proteolytic resistance which have limited the quantity and quality of serum and plasma proteomic analyses in the past. The albumin depletion and low abundance protein enrichment combined method described in the report shows how low abundance enrichment integrated with on-bead digestion offers many workflow advantages such as:
Unique chemically derived beads, AlbuVoid™ is a consumable, one-time use product with no potential for cross-contamination or reduced performance upon regeneration. The report can be downloaded from the company website at: AlbuVoid™ & On-Bead Digestion: Tackling The Challenges Of Serum Proteomics. “We are pleased with these developments as now our users can get Albumin depletion and digestion in one seamless workflow. With these improved and efficient on-bead methods, digestion of serum and plasma samples will become more robust and reproducible. This method can be applied for discovery proteomics, and either label or label-free quantitation.” states Swapan Roy, Ph.D., President and Founder of Biotech Support Group.
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- Ectodomain Shedding and Enrichment of the Soluble Membrane Proteome
- Methods to selectively deplete or purify Hemoglobin from Dried Blood Spots (DBS)
- The Utility of HemoVoid™ is Demonstrated in 3 Proteomic Investigations Identifying Potential Disease Specific Biomarkers
- The 4 common features of our sample prep products, known as the BSG Advantage, are highlighted in a selection of journal references.
- AlbuVoid™ Workflows Advance Cell Secretome Proteomics
- Lipid Removal for Phenotypic Cell Response in Cancer Research
- The Influence of Sample Prep Bias on LC-MS Targeted Peptide Quantification in Serum Proteomics
- Re-imagining proteomics for developing precision medicine biomarkers of the innate immune response in SARS-CoV-2
- Patent Application Describes New Proteomic Methods to Monitor Protease Inhibitor Function During Covid-19 Infections
- Efficient Hemoglobin Removal Advances Red Cell Proteomics Offering Many New Insights Into Inflammation and Infectious Disease
- The Potential for New Blood Biomarkers in the Management of COVID-19 Disease
- Establishing the Utility of HemoVoid™ and HemogloBind™ as Enrichment Tools for Proteomic Analysis of Red Cells and Whole Blood in Parkinson’s Disease
- Species Diversity Supported By BSG Products
- Poster Report Describes Loss of Functional Serpin Activity In Cancer Patient Blood
- AlbuVoid™️ PLUS & AlbuSorb™️ PLUS Evaluating Different Windows of Observation Solves The Many Challenges of Serum Proteomics
- Tackling the Challenges of Serum Proteomics
- Lipid Removal Sample Prep for Cell Response Applications
- Sample Prep for Proteomic Analysis of Saliva
- Biotech Support Group Featured in Book, "Functional Proteomics – Methods and Protocols"
- Sample Prep Liquid Biopsy Products Suitable for Proteomic Profiling of a Variety of Body Fluid Sample Types
- Albumin and High Abundance Depletion
- Using HemogloBind™ as a Hemoglobin Binding Reagent
- Diverse technologies available for researchers to selectively bind or enrich exosomes and extracellular vesicles.
- Stroma Liquid Biopsy™ Biomarkers Profile Pan-Cancer Dysregulation of the Serum Proteome
- Diverse Depletion and Enrichment Technologies Enhance Simplicity and Efficiency of Obtaining Quality Proteomic Information
- Use On-Bead Digestion to Improve Time Required for Serum Digestion
- Using AlbuVoid™ as a Serum Protein Enrichment Kit in Functional Proteomics
- Using Cleanascite™ as a Lipid Absorption and Clarification Reagent
- Using HemoVoid to Remove Hemoglobin Before Analysis
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