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Lipid Removal & Clarification

Laboratory samples prepared for lipid removal and clarification
Cleanascite™ flagship lipid clarification technology

Lipid Removal & Clarification

For the most challenging applications. Cleanascite™ helps reduce lipid-associated matrix effects for cleaner, more reliable downstream research workflows.

Meet Cleanascite™ — Lipid Clarification, Reimagined

Selectively binds lipids while leaving proteins, antibodies, and nucleic acids intact — engineered for proteomics, biomarker discovery, and downstream assay readiness.

Cleanascite™ is designed to reduce lipid-associated matrix effects in challenging biological samples, helping researchers improve sample clarity and downstream analytical performance.

Unlike other solid phases, Cleanascite™ does not have significant protein binding, making its selectivity profile for lipids unique in the bio-research products industry. Its breadth of validated applications is supported by extensive published references.

100+
peer-reviewed citations and references
0
hazardous solvent extraction steps
1
simple suspension-based cleanup workflow
Cleanascite lipid clarification sample preparation
Cleanascite™

Why Cleanascite™ Leads This Category

A practical lipid cleanup solution for complex biological samples without hazardous solvent extraction.

Cost-Effective & Solvent-Free

Replaces hazardous DIY workarounds such as freon, chloroform, and Folch-style extractions with a single suspension reagent. Lower cost per sample, no toxic waste handling, and a faster workflow that fits any lab.

Species-Agnostic Technology

Not derived from immuno-affinity, with high lipid binding capacity and minimal cross-reactivity with proteins and nucleic acids.

Optimized for Challenging Samples

Supports difficult sample types such as serum, plasma, bile, ascites, cell and tissue culture, organ homogenates, and other high lipid content sample matrices.

Compatible with Key Downstream Platforms

Cleanascite™ supports lipid-depleted sample preparation across common proteomics, biomarker, immunoassay, and cell-based research workflows.

LC-MS

LC-MS

Supports lipid-depleted samples for cleaner mass spectrometry analysis.

Array and ELISA-Based Detection

Array and ELISA-Based Detection

Applies to HPLC and bioprocessing workflows where cleaner lipid-depleted samples improve downstream analytical performance.

Immuno-capture Microarrays

Immuno-capture Microarrays

Reduces lipid-associated background in array-based detection workflows.

Cell Response Assays

Cell Response Assays

Supports assay-ready samples where lipid factors may interfere with cell-based readouts.

A Closer Look at the Cleanascite™ Family

Two lipid-clarification workflows, one product family. Toggle between Cleanascite™ for broad sample cleanup and Cleanascite™ LX for highly lipemic serum and plasma.

Cleanascite broad lipid cleanup workflow
Click to enlarge
Flagship product

Cleanascite™

Lipid removal suspension reagent for broad sample cleanup and clarification. Simple. Fast. Reproducible.

View Cleanascite™ Product Page
01

Add sample

Start with serum, plasma, ascites, bile, cell culture, tissue culture, organ homogenate, or another lipid-rich matrix.

02

Add Cleanascite™

Introduce the lipid removal suspension reagent using the recommended sample preparation protocol.

03

Bind & separate

Cleanascite™ binds lipid-associated material while proteins, antibodies, and nucleic acids remain available for analysis.

04

Analyze

Use the clarified sample for LC-MS, ELISA, immuno-capture microarrays, cell response assays, or related research workflows.

Broad Downstream Compatibility

Supports lipid reduction workflows while preserving proteins, antibodies, and nucleic acids for downstream analysis.

Built for Versatility

Our lipid clarification technologies support diverse workflows and sample types.

Serum & Plasma Workflows

Effective for lipid-rich biofluids requiring clarification before downstream analysis.

Cell & Tissue Culture Samples

Useful for reducing lipid-associated interference in complex research sample matrices.

Bulk / Flexible Processing

Adaptable for research workflows ranging from exploratory studies to repeatable laboratory protocols.

Need Help Choosing the Right Lipid Removal Workflow?

Our technical team can help identify the best lipid clarification approach for your sample type, downstream platform, and research goals.

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