Simple. Diverse. Efficient.
Reveal low-abundance biomarkers by removing high-abundance proteins such as albumin and immunoglobulins from serum and plasma.
Our albumin and IgG removal products are powered by the NRicher™ bead chemistry platform — a proteomic sample preparation approach not based on immunoaffinity. These products are designed to simplify albumin and immunoglobulin depletion while supporting downstream proteomic analysis.
Whether for LC-MS proteomics, immunoassays, or functional assays, our diverse and efficient albumin removal solutions help researchers improve access to lower-abundance proteins in serum and plasma workflows.
Sample preparation workflows that expand biomarker discovery into routine healthcare applications.
Designed to support the rapidly expanding installation base of LC-MS instruments and analytical infrastructure.
Compatible across multiple species, enabling consistent proteomic workflows without species-specific limitations.
LC-MS and MALDI workflows
ELISA and Western blot applications
Soluble Proteins and Extracellular Vesicles
Enzyme and biochemical assays
Albumin depletion strategy that captures albumin while recovering low abundance proteins in the flow-through.
Enrichment strategy that captures sub-proteomes directly on bead surfaces.
Combine albumin depletion with IgG removal using integrated Protein A technology.
| Product | Typical Serum Volume per Prep | Recovery Type | Recoverable Protein (µg) | Recommended Applications |
|---|---|---|---|---|
| AlbuSorb™ | 25µl | High recovery | 500–600 µg | LC-MSWestern Blot/ELISAElectrophoresis |
| AlbuSorb™ PLUS | 25µl | High recovery | 500–600 µg | LC-MSElectrophoresis |
| AlbuVoid™ | 100–200 µl | Direct enrichment | 400–500 µg | LC-MSSecretome Analysis |
| AlbuVoid™ PLUS | 50–100 µl | Direct enrichment | 2000–4000 µg | LC-MSSecretome Analysis |
| AlbuVoid™ LC-MS On-Bead | 50–100 µl | On-bead digestion | 1000–2000 µg | LC-MSSecretome Analysis |
Test both workflows with our convenient trial kits to find the perfect solution for your research.
Selectively voids albumin while binding low-abundance proteome.
Albumin and IgG depletion from serum/plasma for proteomics.
Selectively voids albumin, binds low-abundance proteome before LC-MS use.
Selectively binds albumin for albumin depletion from serum/plasma.
Selectively binds albumin and immunoglobulin for deeper depletion.
Try both workflows in one kit to choose the best fit.
Try both PLUS workflows to evaluate albumin + IgG depletion.
Our proprietary bead technology is suitable for multiple formats
Convenient spin column format for rapid processing
Scale up your workflow for automated processing
Flexible format for custom workflows and large volumes
Explore how albumin depletion technologies are applied across proteomics workflows and disease research.
Demonstrates improved detection of low-abundance proteins in secretome analysis workflows.
Read Case StudyBrowse case studies, press releases, and research articles related to our albumin depletion technologies.
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