Mass spectrometry laboratory equipment for proteomics sample preparation

Albumin Removal for Proteomics

Simple. Diverse. Efficient.

Albumin & IgG Removal Kits

Reveal low-abundance biomarkers by removing high-abundance proteins such as albumin and immunoglobulins from serum and plasma.

Our albumin and IgG removal products are powered by the NRicher™ bead chemistry platform — a proteomic sample preparation approach not based on immunoaffinity. These products are designed to simplify albumin and immunoglobulin depletion while supporting downstream proteomic analysis.

Whether for LC-MS proteomics, immunoassays, or functional assays, our diverse and efficient albumin removal solutions help researchers improve access to lower-abundance proteins in serum and plasma workflows.

Cited in Nature & Science. Trusted in proteomics labs since 2010.

Scientist preparing proteomics samples with pipette

Cost Effective & Efficient

Sample preparation workflows that expand biomarker discovery into routine healthcare applications.

Consumable Research Products

Designed to support the rapidly expanding installation base of LC-MS instruments and analytical infrastructure.

Species Agnostic Kits

Compatible across multiple species, enabling consistent proteomic workflows without species-specific limitations.

Typical Workflow for Albumin Removal in Proteomics

Typical proteomics workflow showing albumin and IgG removal steps from serum or plasma, through bead-based depletion, to LC-MS analysis

Serves All Proteomic Analytical Platforms

Mass Spectrometry

LC-MS and MALDI workflows

Immunoassays

ELISA and Western blot applications

Cell Secretome

Soluble Proteins and Extracellular Vesicles

Functional Assays

Enzyme and biochemical assays

Choose Your Workflow

AlbuSorb™

Albumin depletion strategy that captures albumin while recovering low abundance proteins in the flow-through.

AlbuSorb™

AlbuVoid™

Enrichment strategy that captures sub-proteomes directly on bead surfaces.

PLUS Kits

Combine albumin depletion with IgG removal using integrated Protein A technology.

Product Comparison

Product	Typical Serum Volume per Prep	Recovery Type	Recoverable Protein (µg)	Recommended Applications
AlbuSorb™	25µl	High recovery	500–600 µg	LC-MSWestern Blot/ELISAElectrophoresis
AlbuSorb™ PLUS	25µl	High recovery	500–600 µg	LC-MSElectrophoresis
AlbuVoid™	100–200 µl	Direct enrichment	400–500 µg	LC-MSSecretome Analysis
AlbuVoid™ PLUS	50–100 µl	Direct enrichment	2000–4000 µg	LC-MSSecretome Analysis
AlbuVoid™ LC-MS On-Bead	50–100 µl	On-bead digestion	1000–2000 µg	LC-MSSecretome Analysis