NRicher™ Kits
Proteome Enrichment Simplified & Diversified
NRicher™ Mx
General Enrichment for All Biofluids and Tissue Lysates
- Consumable chemically derived beads, species agnostic as they are not derived from antibodies
- Enrich low abundance proteomes from any source, from sera/plasma to cell lysates from both animals and humans, >90% Albumin removal
- Does not require any specialized instruments, just a standard microfuge
- Bead format suitable for automation compatibility, please inquire
- On-Bead digestion for LC-MS analysis, or optional elution for any functional, enzymatic, or immunoassay analysis
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NRicher™ Apo
Enrichment of Apolipoproteins
- Consumable chemically derived beads, species agnostic as they are not derived from antibodies
- Enrich Apolipoproteins from sera or plasma from both animals and humans, >90% Albumin removal
- Does not require any specialized instruments, just a standard microfuge
- Bead format suitable for automation compatibility, please inquire
- On-Bead digestion for LC-MS analysis, or optional elution for any functional, enzymatic, or immunoassay analysis
NRicher™ Ig
Enrichment of all isotypes and subclasses of Immunoglobulins
- Consumable chemically derived beads, species agnostic as they are not derived from antibodies
- Enrich circulating immune complexes from sera or plasma from both animals and humans, >90% Albumin removal
- Does not require any specialized instruments, just a standard microfuge
- Bead format suitable for automation compatibility, please inquire
- On-Bead digestion for LC-MS analysis, or optional elution for any functional, enzymatic, or immunoassay analysis
NRicher™ C
Enrichment of Complement Cascade Related Proteins
- Consumable chemically derived beads, species agnostic as they are not derived from antibodies
- Enrich Complement Cascade related proteins from sera/plasma or cell lysates from both animals and humans, >90% Albumin removal
- Does not require any specialized instruments, just a standard microfuge
- Bead format suitable for automation compatibility, please inquire
- On-Bead digestion for LC-MS analysis, or optional elution for any functional, enzymatic, or immunoassay analysis
Our BSG Advantage
Consumable
Cost-effective, not derived from biologicals
- No specialized instruments or HPLC
- Economical surface chemistries, not derived from biologicals
- No regeneration, so no prep to prep variability
- Simple, fast microfuge bind/wash/elute protocols
On-Bead Digestion
Efficient workflows, quality LC-MS/MS data
- Simple, reproducible workflows
- Equivalent or better than in-solution digestion
- Seamless to LC-MS, no desalting or C18 separations
- Unique proteolytic efficiencies
Enrichment/Depletion
Diverse strategies, species agnostic
- Products support strategies for both enrichment of low abundance proteomes, or depletion of high abundance proteins
- Species agnostic not derived from biologicals
Functional Integrity
Maintained throughout all separations
- Mild buffer conditions maintains native structure with retained enzymatic, functional & bio-activities
- Supports enzyme biomarker assays
- Functional & Chemical Proteomics
- Structural & activity-probe Proteomics
- Top-down & ArrayBridge PEP Proteomics