Press Release

HemoVoid™ Cited in Study of Potential Blood-derived Biomarkers for Parkinson’s Disease

MONMOUTH JUNCTION, NJ, October 6, 2025– A poster presented at the 2025 American Society for Mass Spectrometry (ASMS) Conference, highlights the advantage of HemoVoid™ enrichment. The study from researchers at Stanford University entitled “Parkinson’s Disease biomarker discovery via LC-MS/MS characterization and quantification of alpha synuclein PTMs in erythrocytes” demonstrates an observational advantage of HemoVoid™ enrichment compared to alternatives. 

There is great need for predictive and prognostic Parkinson’s Disease (PD) biomarkers from readily accessible biofluids. Alpha synuclein is highly abundant in erythrocytes and the authors are investigating the prospect of a post-translational (PTM) signature that can distinguish PD from healthy controls.

The study concludes that while alpha synuclein proteoforms are analytically challenging to characterize by Mass Spectrometry, compared to alternatives, the HemoVoid™ on-bead digest sample prep method, detected phospoS87 even in healthy patients.

“The HemoVoid™ product used in this study is one of many beads derived from our unique NRicher™ surface chemistry platform. It is a great example of how bead-based enrichment can be so advantageous, as it simultaneously can improve MS target signal while observing post-translational modifications that are of relatively low abundance compared to the wild type.” stated Dr. Swapan Roy, President and Founder of Biotech Support Group. “Mass Spectrometry opens up the possibility to measure specific protein targets, encompassing a variety of different proteoforms. With our products, future disease research can now be steered towards such proteoform quantifications, using simple and scalable workflows.”

For more information on HemoVoid™, visit:

http://www.biotechsupportgroup.com/HemoVoid-Hemoglobin-Depletion-From-Erythrocytes-p/hvk.htm

For more information of all of our Hemoglobin removal products, visit:

https://www.biotechsupportgroup.com/Hemoglobin-Removal-s/312.htm

For more information on our NRicher™ bead chemistry platform, visit:

https://www.biotechsupportgroup.com/category-s/340.htm

About Biotech Support Group LLC
Biotech Support Group develops innovative sample preparation technologies that address the emerging needs of proteomics, biomarker discovery, and personalized medicine. Flagship products include Cleanascite™ for lipid removal, AlbuVoid™ and AlbuSorb™ PLUS for serum protein depletion, HemogloBind™ and HemoVoid™ for hemoglobin removal, and NRicher™ for low abundance, family specific, and targeted proteome enrichment. These products support translational research by simplifying workflows and improving sample quality for downstream analysis.

For Business Development Inquiries:
Matthew Kuruc
Phone: 732-274-2866
Email: [email protected]

Keywords: HemoVoid™, Hemoglobin depletion, Hemoglobin removal, Parkinson’s Disease, Alpha synuclein, red blood cell proteomics, proteoforms, erythrocyte proteomics,