ProCipitate™ - Protein removal/DNA enrichment & isolation reagent, substitute to phenol/chloroform
- Non-hazardous substitute to phenol/chloroform
- Removes only the contaminants & leaves DNA alone
- Improves yield of DNA over alternative bind and elute systems
- Adaptable to any sample size, and can be automated
- Key component of the ProPrep™ line of application specific kits
ProCipitate™ is a unique protein removal reagent based upon patented elastomeric polyelectrolytes. The polymer chains of ProCipitate™ are initially extended in a high energy state due to an overall net negative charge. When introduced to protein solutions, the charges are neutralized and the polymer chains collapse to a more favorable energy state; DNA and RNA remain unreacted. ProCipitate™ is non-hazardous and can replace phenol/chloroform with the additional benefits of solid-phase suspensions: adaptability to filtration and automation. It is routinely used for plasmids, cosmids, BACs, and genomic DNA, as well as RNA. ProCipitate™ can also be used to remove Proteinase K and other enzymes. ProCipitate™ provides high quality DNA suitable for automated sequencing, southern blotting, and restriction digestion. ProCipitate™ is available as a suspension reagent and in ProPrep™ kits for specific applications and high-throughput 96 well filter formats.
For more information on ProCipitate™ P0050-50 Size & Quantity: 500ml, please contact us
Click here to view ProCipitate™ Product Sheet
U.S. Patent Numbers 5,294,681, 5,453,493 and other patents pending.
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