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BindPro™ For Drug Binding/Screening, Metabolomics and Protein Recovery



 
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Price: $385.00


Product Code: BP355


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Description Applications Specifications
 

Aqueous Protein Crash & Enrichment of Metabolites/Analytes

  • Serum and plasma protein removal, >95%
  • Aqueous buffer system, simplifies analyte concentration
  • Aqueous Protein Crash, linearly scalable, unlike chemical precipitation or membrane filtration.
  • Applicable for drug binding/screening, target analytes and metabolomics
  • Species agnostic, tested species include: human, mouse, sheep, bovine, goat, rat, calf
  • BindPro™ supplied as a suspension reagent; related product - NuGel BindPro™ supplied as a dry powder reagent

BindPro™ is a polymeric protein removal suspension reagent. It is designed as an alternative to ultrafiltration for applications that require a more versatile or scaleable format. BindPro™ also can be used in lieu of solvents for drug binding studies, especially useful for analytes that are water soluble. Consequently, BindPro™ has applications in a range of drug binding, screening and metabolomic investigations. If desired, protein can be recovered using moderately alkaline conditions.


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References

Lipoproteins

Turner, Joseph D., R. Stuart Langley, Kelly L. Johnston, Katrin Gentil, Louise Ford, Bo Wu, Maia Graham et al. "Wolbachia lipoprotein stimulates innate and adaptive immunity through Toll-like receptors 2 and 6 to induce disease manifestations of filariasis." Journal of Biological Chemistry 284, no. 33 (2009): 22364-22378.

Patent

Bhogal, John, Shridhara Alva Karinka, Timothy P. Henning, David Cunningham, Udo Hoss, Andrew H. Naegeli, and John Latour. "Methods of Collecting and Analyzing Samples." U.S. Patent 20,120,296,189, issued November 22, 2012.